Where is the codon located
What is Codon and Anti-Codon ? Difference and Working Explained
we always use the terms like codon
anticodon when we are at the end of gene
expression like at the time of
translation when we discuss the
translation process or when we discuss
the molecular structure of tRNA and mRNA
molecules so what activity do mr. note
what order on an anticodon is we'll be
discussing in this like your so let's
get started first of all we will see the
overview in simple terms we say codon is
a three base sequence of nitrogenous
bases in a row or messenger RNA so we
know that mRNA is a single stranded
molecule of poly nucleotide and these
poly nucleotides are adenine guanine
cytosine and uracil timing is not
available here which is present in DNA
but here in a state of timing we have a
uracil here in mRNA mold or animal do
simply so we define this codon it's a
three base sequence of any of the above
nucleotides it it may be a GC GC a but
only at three nucleotide sequence like
Aug defined initiation codon for me Tony
but if we take an example Aug a sequence
it defines nothing so it is the three
base sequences define something these
codes for something and the something
here is the amino acid and similarly we
say anticodon is a three base sequence
of nitrogenous bases it goes the same
way it's also the three basic means of
nitrogenous bases but it's on tRNA at a
specific loop old anticodon loop it must
be noted here anticodon is present only
at anticodon loop nowhere else in the
trna molecule because trna has got
another group also and remember tRNA has
not only adenine tiny Gani and uracil
bases but it is also zero basis we do
not account for
anticodon and we must remember here
Sandra has message or information in
these codons in these three basic
sequence what we called as codon and in
these codons what is in these : its
which emulation is to be made which a -
is to be added to their growing
polynucleotide chain so specific codon
codes for specific amino acid and tRNA
being the Gator here it actually cater
here that is it just carries amino acids
to the ribosome where translation is
under process
so here the anticodon present on t army
makes sure that the correct amino acid
is getting added to the chain when it's
complimentary sequence matches it codon
so we called it a and decode on let's
take an example of codon here where
codon Aug sequence that's a denis
followed by uracil is followed by goning
it's a sequence of three nucleotide
bases and this one codes for mutual mean
and it's also an initiation codon so it
calls for me Tony
and for that anticodon sequence must be
you AC because it says complimentary
sequence to the codon it's the anticodon
and this sequence will be present on
tRNAs till now all 64 codons which have
been discovered or present on mRNA chain
and of these 64 codons 61 codons code
for specific amino acid and the three
remaining codons or stop codons they do
not call for any mi nurses they are a
stop signal where this amino acid chain
is to be stopped where this termination
has to occur now we will see where we
encounter with these codons that
anticodons
we encounter with these codons
anticodons
at the time of translation and died - at
the time of amino acid activation and
for this amino acid activation we have a
first step by amino acid it may be any
amino acid combining with ATP and it
gives us a minor SL MB plus two
phosphate and a minus L M
he has combined with tyranny because
tRNA is the molecule that will carry
this amino acid to the ribosome so it
combines with tRNA and gives us a
cognate DNA or charges DNA there to
khones MRSS trna so now we're the trna
loaded with amino acid this is called as
cognate DNA or charge it in and this
will go to the ribosome and will match
with it is codon now let's see in detail
how these codons anticodons match with
each other
and where these anticodons and codons
are suppose we have an mRNA chain here
it has got a series of nucleotides and
for that we have a specific nucleotide
sequence of three nucleotide bases
that's you see a you wrestle cytosine
and adenine and uracil cytosine and
adding is present on mRNA and this is
code for selling amino acid so it must
be noted here you see a it goes for
serine amino acid now for that selling
codon that's present on mRNA there must
be any cognate tRNA this will bring the
setting a minor I said to the growing
chain and this cognate tRNA discharges
tRNA will only add serine a minor I said
to the growing chain then it's three
base sequence present on anticodon loop
complimentary matches the three base
sequence on mRNA remember here so this
is a sort of product a minor acid
recognization here type tRNA if PR and
in sequence matches with the sequence of
mRNA three base pairs then it adds a -
it otherwise it will never add a minor
sis - it's a sort of reorganization here
and we see here on cognate tRNA where a
sequence of a GU for this serene
codon and it complimentary matches with
you see a so at three base sequence on
tRNA is anticodon and a three base
sequence on mRNA codon and both are
complete
with each other and you must remember
here that anticodon is reading 3 prime
to 5 Prime and while as codon is read in
5 prime to 3 prime end and on tRNA
molecule we see different type of loops
like we have a deal loop we have a
t-cell loop variable loop that contains
mostly the serial braces and anticodon
loop that contains this 3 base sequence
what we called an anticodon that's why
it is called anticodon loop and on the
upper side we have an acceptor system
that has got a minor acid install it
onto it which will add to the growing
chain and one last thing that must be in
your mind is white termination codons
like UGA UAE sequence on M R in a
terminal translation process terminate
the synthesis process so the answer is
it's only and only because a termination
codon present on mRNA does not have any
cognate kill me or charged tRNA what I
mean to say here is its anticodon is
nowhere in the process to add amino acid
to the chain so time is the codon
the termination codon present on mRNA is
devoid of any anticodon drug
organization because of the absence of
charged DNA we terminate the synthesis
and that's why it's called termination
or stop chorus so this was all about the
concept of codon and anticodon I hope
you like a video if you liked it give it
a thumbs up and make sure to subscribe
this channel
Thanks
