What is Codon and Anti-Codon ? Difference and Working Explained

we always use the terms like codon

anticodon when we are at the end of gene

expression like at the time of

translation when we discuss the

translation process or when we discuss

the molecular structure of tRNA and mRNA

molecules so what activity do mr. note

what order on an anticodon is we'll be

discussing in this like your so let's

get started first of all we will see the

overview in simple terms we say codon is

a three base sequence of nitrogenous

bases in a row or messenger RNA so we

know that mRNA is a single stranded

molecule of poly nucleotide and these

poly nucleotides are adenine guanine

cytosine and uracil timing is not

available here which is present in DNA

but here in a state of timing we have a

uracil here in mRNA mold or animal do

simply so we define this codon it's a

three base sequence of any of the above

nucleotides it it may be a GC GC a but

only at three nucleotide sequence like

Aug defined initiation codon for me Tony

but if we take an example Aug a sequence

it defines nothing so it is the three

base sequences define something these

codes for something and the something

here is the amino acid and similarly we

say anticodon is a three base sequence

of nitrogenous bases it goes the same

way it's also the three basic means of

nitrogenous bases but it's on tRNA at a

specific loop old anticodon loop it must

be noted here anticodon is present only

at anticodon loop nowhere else in the

trna molecule because trna has got

another group also and remember tRNA has

not only adenine tiny Gani and uracil

bases but it is also zero basis we do

not account for

anticodon and we must remember here

Sandra has message or information in

these codons in these three basic

sequence what we called as codon and in

these codons what is in these : its

which emulation is to be made which a -

is to be added to their growing

polynucleotide chain so specific codon

codes for specific amino acid and tRNA

being the Gator here it actually cater

here that is it just carries amino acids

to the ribosome where translation is

under process

so here the anticodon present on t army

makes sure that the correct amino acid

is getting added to the chain when it's

complimentary sequence matches it codon

so we called it a and decode on let's

take an example of codon here where

codon Aug sequence that's a denis

followed by uracil is followed by goning

it's a sequence of three nucleotide

bases and this one codes for mutual mean

and it's also an initiation codon so it

calls for me Tony

and for that anticodon sequence must be

you AC because it says complimentary

sequence to the codon it's the anticodon

and this sequence will be present on

tRNAs till now all 64 codons which have

been discovered or present on mRNA chain

and of these 64 codons 61 codons code

for specific amino acid and the three

remaining codons or stop codons they do

not call for any mi nurses they are a

stop signal where this amino acid chain

is to be stopped where this termination

has to occur now we will see where we

encounter with these codons that


we encounter with these codons


at the time of translation and died - at

the time of amino acid activation and

for this amino acid activation we have a

first step by amino acid it may be any

amino acid combining with ATP and it

gives us a minor SL MB plus two

phosphate and a minus L M

he has combined with tyranny because

tRNA is the molecule that will carry

this amino acid to the ribosome so it

combines with tRNA and gives us a

cognate DNA or charges DNA there to

khones MRSS trna so now we're the trna

loaded with amino acid this is called as

cognate DNA or charge it in and this

will go to the ribosome and will match

with it is codon now let's see in detail

how these codons anticodons match with

each other

and where these anticodons and codons

are suppose we have an mRNA chain here

it has got a series of nucleotides and

for that we have a specific nucleotide

sequence of three nucleotide bases

that's you see a you wrestle cytosine

and adenine and uracil cytosine and

adding is present on mRNA and this is

code for selling amino acid so it must

be noted here you see a it goes for

serine amino acid now for that selling

codon that's present on mRNA there must

be any cognate tRNA this will bring the

setting a minor I said to the growing

chain and this cognate tRNA discharges

tRNA will only add serine a minor I said

to the growing chain then it's three

base sequence present on anticodon loop

complimentary matches the three base

sequence on mRNA remember here so this

is a sort of product a minor acid

recognization here type tRNA if PR and

in sequence matches with the sequence of

mRNA three base pairs then it adds a -

it otherwise it will never add a minor

sis - it's a sort of reorganization here

and we see here on cognate tRNA where a

sequence of a GU for this serene

codon and it complimentary matches with

you see a so at three base sequence on

tRNA is anticodon and a three base

sequence on mRNA codon and both are


with each other and you must remember

here that anticodon is reading 3 prime

to 5 Prime and while as codon is read in

5 prime to 3 prime end and on tRNA

molecule we see different type of loops

like we have a deal loop we have a

t-cell loop variable loop that contains

mostly the serial braces and anticodon

loop that contains this 3 base sequence

what we called an anticodon that's why

it is called anticodon loop and on the

upper side we have an acceptor system

that has got a minor acid install it

onto it which will add to the growing

chain and one last thing that must be in

your mind is white termination codons

like UGA UAE sequence on M R in a

terminal translation process terminate

the synthesis process so the answer is

it's only and only because a termination

codon present on mRNA does not have any

cognate kill me or charged tRNA what I

mean to say here is its anticodon is

nowhere in the process to add amino acid

to the chain so time is the codon

the termination codon present on mRNA is

devoid of any anticodon drug

organization because of the absence of

charged DNA we terminate the synthesis

and that's why it's called termination

or stop chorus so this was all about the

concept of codon and anticodon I hope

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